SOCS3 Monoclonal Antibody

SKU: BT-MCA4817

Size:100μL

Background:This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Research_area:Signal transduction, Epigenetics and nuclear signaling, Cancer, Stem cells, Metabolism, Immunology

Target_protein:SOCS3

applications:IHC, ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5E12E7F1

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:SOCS3

Immunogen:Purified recombinant fragment of human SOCS3 (AA: 1-225) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):24.8KDa

UniProt accession:O14543

Synonyms:CIS3, SSI3, ATOD4, Cish3, SSI-3, SOCS-3

GeneID:9021