Snaclec rhodocytin subunit alpha Antibody, HRP conjugated - Cat. #: CSB-PA888242LB01CBG

SKU: CSB-PA888242LB01CBG

Size :50ug

Clone Number:

Aliases:antibody; Snaclec rhodocytin subunit alpha antibody; Aggretin alpha chain antibody; Rhodoaggretin subunit alpha antibody

Product Type:Polyclonal Antibody

Immunogen Species:Calloselasma rhodostoma (Malayan pit viper) (Agkistrodon rhodostoma)

UniProt ID:Q9I841

Immunogen:Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit alpha protein (1-136AA)

Raised in:Rabbit

Species Reactivity:Calloselasma rhodostoma

Tested Applications:ELISA

Background:Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:

Research Areas:Others