SMRTe Polyclonal Antibody

SKU: BT-AP08413

Size:100μL

Background:NCOR2 (nuclear receptor corepressor 2) encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of NCOR2 is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:NCOR2

applications:IHC-p, IF, WB, ELISA

Reactivity:Human

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:SMRTe Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):274034

UniProt accession:Human: Q9Y618; Mouse: Q9WU42

Synonyms:NCOR2; CTG26; Nuclear receptor corepressor 2; N-CoR2; CTG repeat protein 26; SMAP270; Silencing mediator of retinoic acid and thyroid hormone receptor; SMRT; T3 receptor-associating factor; TRAC; Thyr

GeneID:Human: 9612