SMN antibody , Cat. # FNab08033

SKU: FNab08033

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:3D2

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:The survival of motor neurons(SMN) genes are the disease genes of spinal muscular atrophy(SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein. This antibody can recognize human,mouse and rat SMN.

Immunogen:survival of motor neuron 2, centromeric

Synonyms:C BCD541, Component of gems 1, FLJ76644, Gemin 1, SMN, SMN1, SMN1,SMN, SMN2, SMNC, SMNT, Survival motor neuron protein

Observed MW:38kd

Uniprot ID:Q16637

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IF

Recommended dilution:WB: 1:1000-1:6000; IF: 1:50-1:500

Gene ID:

Research Area:Neuroscience, Metabolism