SMG5 antibody , Cat. # FNab08025

SKU: FNab08025

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A(PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.

Immunogen:Smg-5 homolog, nonsense mediated mRNA decay factor

Synonyms:EST1 like protein B, EST1B, hSMG 5, KIAA1089, LPTS interacting protein, LPTS RP1, LPTSRP1, Protein SMG5, RP11 54H19.7, SMG 5, SMG 5 homolog, SMG5

Observed MW:114 kDa

Uniprot ID:Q9UPR3

Reactivity:Human

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:2000

Gene ID:23381

Research Area:Epigenetics