SKP1 Monoclonal Antibody

SKU: BT-MCA4771

Size:100μL

Background:This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Research_area:Cell Biology

Target_protein:SKP1

applications:WB, IHC, ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:4E11

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:SKP1

Immunogen:Purified recombinant fragment of human SKP1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):19kDa

UniProt accession:P63208

Synonyms:OCP2, p19A, EMC19, SKP1A, OCP-II, TCEB1L, MGC34403

GeneID:6500