Serpina1 Polyclonal Antibody

SKU: D-AB-10209L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:Serpina1

Target Synonym:A1A;A1AT;A1AT;AAT;Alpha 1 antiproteinase;Alpha 1 antitrypsin;Alpha 1 antitrypsin null;Alpha 1 protease inhibitor;Alpha-1 protease inhibitor;Alpha-1-antiproteinase;alpha1 proteinase inhibitor;Alpha1AT;Dom1;PI;PI1;PRO2275;Serine (or cysteine) proteinase inhibitor clade A member 1;Serine protease inhibitor 1-1;Serine protease inhibitor A1a;Serpin A1;Serpin A1a;Serpin peptidase inhibitor clade A member 1;Serpina1;Short peptide from AAT;SPAAT;Spi1-1

Research Areas:Cancer;Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P17475

Accession:

Background:SERPINA1 is the gene for a protein called alpha-1-antitrypsin (AAT),which is a serine protease inhibitor whose targets include elastase,plasmin,thrombin,trypsin,chymotrypsin,and plasminogen activator. AAT is a glycoprotein synthesized primarily by hepatocytes,with smaller amountssynthesized by intestinal epithelial cells,neutrophils,pulmonary alveolar cells and macrophages. AAT is the most abundant,endogenous serine protease inhibitor in blood circulation and it has been implicated in regulating vital fluid phase biological events such as blood coagulation,fibrinolysis,complement activation,apoptosis,reproduction,tumor progression and inflammatory response. The primary function of AAT is thought to be the inactivation of neutrophil elastase and other endogenous serine proteases. Defects in SERPINA1 can cause emphysema or liver disease.

Concentration:1 mg/mL

Immunogen:Recombinant Rat Serpina1 protein expressed by E.coli

Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:500-1000

Calculated MW:46kDa

ObservedMW:43kDa,50kDa