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Gene Bio Systems

SCN5A Antibody - Cat. #: CSB-PA280563

SCN5A Antibody - Cat. #: CSB-PA280563

CSB-PA280563

£515.00 GBP
£515.00 GBP
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Size :100ul

Clone Number:

Aliases:Cardiac tetrodotoxin insensitive voltage dependent sodium channel alpha subunit antibody; CDCD2 antibody; CMD1E antibody; CMPD2 antibody; HB1 antibody; HB2 antibody; HBBD antibody; HH1 antibody; ICCD antibody; IVF antibody; LQT3 antibody; PFHB1 antibody; Scn5a (gene name) antibody; Scn5a antibody; SCN5A_HUMAN antibody; Sodium channel protein cardiac muscle alpha subunit antibody; Sodium channel protein cardiac muscle subunit alpha antibody; Sodium channel protein type 5 subunit alpha antibody; Sodium channel protein type V alpha subunit antibody; Sodium channel protein type V subunit alpha antibody; SSS1 antibody; VF1 antibody; Voltage gated sodium channel alpha subunit Nav1.5 antibody; Voltage-gated sodium channel subunit alpha Nav1.5 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q14524

Immunogen:Synthesized peptide derived from Human sodium channel.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na+ channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels.

Sebastian K.G. Maier, Circulation, Mar 2004; 109: 1421 - 1427.
T.R. Cummins, Neurology, Jan 2003; 60: 224 - 229.
Christopher A. Ahern, Circ. Res., May 2005; 96: 991 - 998.
Jyoti Dhar Malhotra, Circulation, Mar 2001; 103: 1303 - 1310.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SCN5A

Research Areas:Neuroscience;Cardiovascular

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