SAV1 Polyclonal Antibody

SKU: E-AB-19264

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: SAV1

Target Synonym: 1700040G09Rik;45 kDa WW domain protein;hWW 45;hWW45;Protein salvador homolog 1;salvador family WW domain containing protein 1;salvador homolog 1 (Drosophila);Salvador homolog 1;Salvador; Drosophila; homolog of;SAV 1;SAV;SAV1;SAV1;WW 45;WW domain containing;WW domain-containing adaptor 45;WW domain-containing protein; 45-KD;WW45;WW45 protein;WWP 4;WWP4

Research Areas: Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9H4B6

Accession:

Background: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

Concentration: 1.32 mg/mL

Immunogen: Fusion protein of human SAV1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:100-1:300

Calculated MW:

ObservedMW: