RSK3(Phospho Thr353) Rabbit Polyclonal Antibody

SKU: BT-AP04554

Size:100μL

Background:Catalytic activity:ATP + a protein = ADP + a phosphoprotein.|cofactor:Magnesium.|enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.|Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.|PTM:Autophosphorylated on Ser-377| as part of the activation process.|Belongs to the protein kinase superfamily.|Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.|Contains 1 AGC-kinase C-terminal domain.|Contains 2 protein kinase domains.|subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.|tissue specificity:Expressed in many tissues. Highest expression in lung and skeletal muscle.|

Research_area:Epigenetics and nuclear signaling; Signal transduction

Target_protein:RPS6KA2

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:RSK3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):80630

UniProt accession:Human: Q15349; Mouse: Q9WUT3

Synonyms:RSK3 ;Phospho Thr353; Ribosomal protein S6 kinase alpha-2; S6K-alpha-2; EC 2.7.11.1; 90 kDa ribosomal protein S6 kinase 2; p90-RSK 2; p90RSK2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; Ribosomal S6 kinase 3; RSK-3; pp90RSK3

GeneID:Human: 6196; Mouse: 20112