RNF6 Antibody - Cat. #: CSB-PA897080LA01HU

SKU: CSB-PA897080LA01HU

Size :50ug

Clone Number:

Aliases:E3 ubiquitin-protein ligase RNF6 antibody; Ring finger protein (C3H2C3 type) 6 antibody; Ring finger protein 6 antibody; RING H2 protein antibody; RING H2 protein RNF6 antibody; RNF 6 antibody; RNF6 antibody; RNF6_HUMAN antibody; SPG2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y252

Immunogen:Recombinant Human E3 ubiquitin-protein ligase RNF6 protein (1-298AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IF; Recommended dilution: IF:1:50-1:200

Background:E3 ubiquitin-protein ligase mediating \'Lys-48\'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates \'Lys-6\' and \'Lys-27\'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RNF6

Research Areas:Cell biology