RN213 rabbit pAb

SKU: ES13369

Size: 100μL

Source:Rabbit

Applications:IHC;IF

Reactivity:Human; Mouse

Dilution:IHC-p 1：50-200

Immunogen:Synthesized peptide derived from human RN213. AA range:307-407

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:57674

Human_swiss_prot_no:Q63HN8

Subcellular_location:Cytoplasm, cytosol . Lipid droplet .

Other_name:

Background:This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],