Recombinant YB-1 Monoclonal Antibody

SKU: AN301185L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:YB-1

Target Synonym:YBX;CSDA;MDR-NF;YBX1;BP-8;CBF-A;CSDA2;CSDB;DBPB;EFI-A;MDR-NF1;NSEP-1;NSEP1;YB-1;YB1;BP 8;CCAAT binding transcription factor I subunit A;CCAAT-binding transcription factor I subunit A;DNA binding protein B;DNA-binding protein B;Enhancer factor I subunit A;MDR NF1;MGC104858;MGC110976;MGC117250;NSEP 1;Nuclease sensitive element binding protein 1;Nuclease-sensitive element-binding protein 1;p50;Q15905;YB 1;Y-box binding protein 1;Y-box transcription factor;YBOX1;Y-box-binding protein 1;YBX 1;YB-1

Research Areas:Tags & Cell Markers;Epigenetics and Nuclear Signaling;Stem Cells;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:9D11

UNIProt ID:P67809

Accession:

Background:This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human YB-1 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000;WB 1:2000-1:10000

Calculated MW:36 kDa

ObservedMW:49 kDa