Recombinant VAV3 Monoclonal Antibody

SKU: AN301844L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:VAV3

Target Synonym:VAV;VAV3

Research Areas:Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A556

UNIProt ID:Q9UKW4

Accession:

Background:Vav proteins belong to the Dbl family of guanine nucleotide exchange factors (GEFs) for Rho/Rac small GTPases. The three identified mammalian VAV proteins (VAV1, VAV2 and VAV3) differ in their expression. Vav1 is expressed only in hematopoietic cells and is involved in the formation of the immune synapse. VAV2 and VAV3 are more ubiquitously expressed. VAV proteins contain the Dbl homology domain, which confers GEF activity, as well as protein interaction domains that allow them to function in pathways regulating actin cytoskeleton organization.

Concentration:1 mg/mL

Immunogen:Recombinant human VAV3 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000

Calculated MW:98 kDa

ObservedMW:98 kDa