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GeneBio Systems

Recombinant TNF receptor II Monoclonal Antibody

Recombinant TNF receptor II Monoclonal Antibody

AN301888L

£302.00 GBP
£302.00 GBP
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Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:TNF receptor II

Target Synonym:soluble TNFR1B variant;Tumor necrosis factor receptor;tumor necrosis factor binding protein;CD120b;TBPII;TNF-R-II;TNF-R75;TNFBR;TNFR1B;TNFR2;TNFR80;p75;p75TNFR;TNF Receptor II;TNFRSF1B;p80 TNF-alpha receptor;Tumor Necrosis Factor Receptor II;Etanercept;P75tbpii;TNF-R2;TNFR2TNFR1B;TNFRII;TNF-RII;TNFR-II;CD120b antigen;p75 TNF receptor;soluble TNFR1B variant 1;TNF RII;TNFBRp80 TNF-alpha receptor;tumor necrosis factor beta receptor;tumor necrosis factor binding protein 2;Tumor necrosis factor receptor 2;tumor necrosis factor receptor superfamily member 1B;tumor necrosis factor receptor superfamily;member 1B;Tumor necrosis factor receptor type II;p80;Tumor Necrosis Factor Receptor II

Research Areas:Cell Biology;Immunology;Signal Transduction;Cancer;Cardiovascular;Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC;IF

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A604

UNIProt ID:P20333

Accession:

Background:TNF receptor II (TNF-R2) is one of the receptors of TNF-α. The two receptors for TNF-α, TNF-R1 (55 kDa) and TNF-R2 (75 kDa), can mediate distinct cellular responses. In most cases, cytotoxicity elicited by TNF has been reported to act through TNF-R1. In contrast, TNF-R2 appears to be important in T cell signaling and responses to infection. TNF-R2 binds to distinct members of the TRAF family, leading to the activation of NF-κB. Soluble forms of both receptors have also been characterized which can bind TNF-α and may play an important role in immune disorders.

Concentration:1 mg/mL

Immunogen:Recombinant human TNF receptor II fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:100;IF 1:50

Calculated MW:48 kDa

ObservedMW:63 kDa

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