Recombinant TFF1/pS2 Monoclonal Antibody

SKU: AN301892L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:TFF1/pS2

Target Synonym:TFF;pNR;HPS;D21S;Protein Ps;Trefoil factor;TFF1;BCEI;D21S21;HP1.A;HPS2;pNR-2;pS2;Breast cancer estrogen-inducible protein;Polypeptide P1.A;Protein Ps2;Trefoil factor 1

Research Areas:Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A608

UNIProt ID:P04155

Accession:

Background:TFF1/pS2 is a gastric peptide that is highly expressed by mucosal goblet cells of the stomach, where it is thought to play a role in maintaining the integrity of the epithelial layer of the mucosa through the regulation of cell-cell adhesion and cell migration. Research studies have shown that TFF1 functions as a tumor suppressor in the stomach as its expression is frequently lost in gastric carcinomas, largely due to promoter hypermethylation. Research studies have also demonstrated that TFF1 is a transcriptional target of estrogen receptor-α and that TFF1 expression in breast carcinoma may be used as a predictive biomarker for response to anti-estrogen therapy.

Concentration:1 mg/mL

Immunogen:Recombinant human TFF1/pS2 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000;IHC 1:50-1:100

Calculated MW:10 kDa

ObservedMW:13 kDa