Recombinant Streptokinase protein

SKU: CD00011

Size:20 ug

Background:Streptokinase is a thrombolytic agent i.e. it dissolves vascular thrombi. This potent agent is derived from the beta haemolytic streptococci and is consequently associated with the risk of anaphylaxis. Streptokinase acts by stimulating the conversion of plasminogen to plasmin. It’s a proteolytic enzyme which is able to disrupt fibrin stability and production. The half-life of streptokinase is 6 hours.

Research_area:Others

Purity:> 97 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Streptokinase

Biological activity:Fully biologically active when compared to standard. The specific activity determined by fibrining lysis in agarose plate is 8. × 14 IU/mg.

Synonyms:Streptokinase, ska,Recombinant

Endotoxin:Less than 1 EU/μg of rSK as determined by LAL method.

Storage:-20ºC

Sequence:IAGPEWLLDR PSVNNSQLVV SVAGTVEGTN QDISLKFFEI DLTSRPAHGG KTEQGLSPKS KLFATDSGAM PHKLEKADLL KAIQEQLIAN VHSNDDYFEV IDFASDATIT DRNGKVYFAD KDGSVTLPIQ PVQEFLLKGH VRVRPYKEKP VQNQAKSVDV EYTVQFTPLN PDDDFRPALK DTKLLKTLAI GDTITSQELL AQAQSILNKN HPGYTIYERD SSIVTHDNDI FR

uniprot accession:P779

Molecular weight:Approximately 47.3 kDa, a single non-glycosylated polypeptide chain containing 414 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in PBS, pH 7.4.