Recombinant Staphylokinase protein

SKU: CD00013

Size:20 ug

Background:Staphylokinase is an amino acid enzyme secreted by several species of streptococci. It is a 16 kDa potent plasminogen activator that converts plasminogen into plasmin which can digest fibrin the major constituent of blood thrombi. SAK forms 1:1 complex with plasmin, which is a positive feedback of producing other complexes. Recent studies on the thrombolytic potential of recombinant SAK in achieving early perfusion in myocardial infarction and in the dissolution of platelet-rich clot have clearly established its immense utility in clinical medicine as a thrombolytic agent and suggested that it can be developed as a potent clot-dissolving agent.

Research_area:Others

Purity:> 97% by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Staphylokinase

Biological activity:Fully biologically active when compared to standard. The specific activity determined by fibrining lysis in agarose plate is 5. × 14 IU/mg.

Synonyms:SAK, Recombinant

Endotoxin:Less than 1 EU/μg of rSAK as determined by LAL method.

Storage:-20ºC

Sequence:SSSFDKGKYK KGDDASYFEP TGPYLMVNVT GVDGKRNELL SPRYVEFPIK PGTTLTKEKI EYYVEWALDA TAYKEFRVVE LDPSAKIEVT YYDKNKKKEE TKSFPITEKG FVVPDLSEHI KNPGFNLITK VVIEKK

uniprot accession:P6882

Molecular weight:

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in PBS, pH 7.4.