Recombinant ROCK2 Monoclonal Antibody

SKU: AN301649L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:ROCK2

Target Synonym:KIAA;Rho kinase;Rho-associated protein kinase;ROCK2;ROCK-II;Rho kinase 2;Rho-associated;Rho-associated protein kinase 2;ROCK 2;Rock II;Rock2m;ROK alpha;ROKalpha;KIAA0619;B230113H15Rik;coiled coil containing protein kinase II;coiled-coil-containing protein kinase 2;mKIAA0619;p164 ROCK 2;p164 ROCK-2;Rho associated;Rho associated coiled coil containing protein kinase 2;Rho associated protein kinase 2;Rho-kinase

Research Areas:Cell Biology;Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC;IF;IP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A352

UNIProt ID:O75116

Accession:

Background:Rho associated coiled-coil containing protein kinase 2 is a protein that in humans is encoded by the ROCK2 gene. Fasudil is an inhibitor of ROCK protein.The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.

Concentration:1 mg/mL

Immunogen:Recombinant human ROCK2 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:5000;IHC 1:50-1:100;IF 1:50;IP 1:25

Calculated MW:160 kDa

ObservedMW:190-200 kDa