Recombinant Rat KLK6 Protein (His Tag)

SKU: PDER100152

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:KLK6

Target Synonym:Bssp;KLK 6;KLK6;KLK9;Kallikrein 6 precursor;Kallikrein related peptidase 6;Kallikrein-6;Kallikrein6;Klk29;Klk6;Klk7;MGC9355;MSP;Neurosin;PRSS 18;PRSS 9;PRSS18;PRSS9;Protease M;Protease serine 18;Protease serine 9;Serine prote;hK 6;hK6;mGK 1;mGK1

Research Areas:

Conjugation:

Target Species:Rat

Expression Host:E.coli

Application:

Fusion tag:N-His

UNIProt ID:P36374

Accession:P36374-1

Background:Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

Concentration:

Activity:Not validated for activity

Sequence:Ile25-Pro261

Purity: > 80% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:26.3 kDa

ObservedMW:28.62 kDa