Recombinant Rat IL-2 Protein(GST Tag)

SKU: PDER100142

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Cytokines

Abbreviation:IL-2

Target Synonym:POIL;Aldesleukin;Interleukin-2;Involved in regulation of T cell clonal expansion;POIL2;T-cell growth factor;IL 2;IL2;lymphokine;TCGF;interleukin 2;T cell growth factor;Il-2

Research Areas:Cancer;Immunology;Cell Biology;Signal Transduction

Conjugation:

Target Species:Rat

Expression Host:E.coli

Application:

Fusion tag:N-GST

UNIProt ID:P17108

Accession:P17108

Background:IL-2 (Interleukin 2) is a critical cytokine in T cell biology. It promotes T cell activation and expansion, the development, maintenance and function of regulatory T cells (Treg), and the differentiation of CD8+ T cells into terminal effector cells and memory cells. IL-2 signals through a receptor complex composed of CD25/IL-2 R alpha, IL-2 R beta, and the Common gamma Chain (gamma c). IL-2 R beta is also a component of the IL-15 receptor complex. Gamma c is also a signaling subunit in the receptors for IL-4, -7, -9, -15, and -21.

Concentration:

Activity:Not validated for activity

Sequence:Ala21-Gln155

Purity:> 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method

Calculated MW:40.8 kDa

ObservedMW:42 kDa