Recombinant PPM1A Monoclonal Antibody

SKU: AN301633L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:PPM1A

Target Synonym:PPM1A;PP2C-ALPHA;PP2CA;PP2Calpha;Protein Phosphatase 1A;Protein Phosphatase 2C Isoform Alpha;Protein Phosphatase IA;PPPM1A

Research Areas:Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A336

UNIProt ID:P35813

Accession:

Background:Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.

Concentration:1 mg/mL

Immunogen:Recombinant human PPM1A fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:100

Calculated MW:42 kDa

ObservedMW:42 kDa