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GeneBio Systems

Recombinant PKM Monoclonal Antibody

Recombinant PKM Monoclonal Antibody

AN301098L

£256.00 GBP
£256.00 GBP
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Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:PKM

Target Synonym:OIP;THBP;HEL-S;CTHBP;HEL-S-30;OIP3;PK3;PKM2;TCB;THBP1;PKM;p58;PK2;CTHBP;OIP3;p58;PKM2;TCB;THBP1;Cytosolic thyroid hormone binding protein;Cytosolic thyroid hormone-binding protein;Cytosolic thyroid hormone-binding protein (CTHBP);KPYM;MGC3932;muscle 2;muscle type;OIP 3;OIP-3;OPA interacting protein 3;Opa-interacting protein 3;Opa-interacting protein 3 (OIP-3);PK muscle type;pykm;Pyruvate kinase;Pyruvate kinase 2/3;Pyruvate kinase 3;Pyruvate kinase isozymes M1/M2;pyruvate kinase M1/2;Pyruvate kinase muscle;Pyruvate kinase muscle isozyme;pyruvate kinase PKM;Threonine-protein kinase PKM2;Thyroid hormone binding protein 1;Thyroid hormone binding protein cytosolic;Thyroid hormone-binding protein 1;Thyroid hormone-binding protein 1 (THBP1);Tumor M2 PK;Tumor M2-PK;PKM2

Research Areas:Signal Transduction;Epigenetics and Nuclear Signaling;Cancer;Metabolism;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6A7

UNIProt ID:P14618

Accession:

Background:This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human PKM protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1000;WB 1:1000-5000

Calculated MW:57 kDa

ObservedMW:57 kDa

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