Recombinant PKC zeta Monoclonal Antibody

SKU: AN301942L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:PKC zeta

Target Synonym:PKC;PRKCZ;PKC-ZETA;PKC2;14-3-3-zetaisoform;AI098070;aPKCzeta;C80388;EC 2.7.11.13;included;KPCZ;nPKC zeta;nPKC-zeta;OTTHUMP00000001368;OTTHUMP00000044160;PKC 2;PKC ZETA;Pkcz;PKC-Z;PKCZETA;PKM-zeta;Protein kinase C zeta;Protein kinase C zeta form;Protein kinase C zeta type;Protein Kinase M Zeta;r14-3-3;R74924;zetaPKC

Research Areas:Signal Transduction;Cancer;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A658

UNIProt ID:Q05513

Accession:

Background:Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC.

Concentration:1 mg/mL

Immunogen:Recombinant human PKC zeta fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000

Calculated MW:68 kDa

ObservedMW:70 kDa