Recombinant Phospho-Tau (Ser199) Monoclonal Antibody

SKU: AN302079L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies;Acetyl/Phospho/Methyl Antibodies

Abbreviation:Phospho-Tau (Ser199)

Target Synonym:FTDP;PPP1R;DDPAC;FTDP-17;MAPTL;MSTD;MTBT1;MTBT2;PPND;PPP1R103;TAU;MAPT;Microtubule-Associated Protein Tau;Neurofibrillary Tangle Protein;Paired Helical Filament-Tau;PHF-Tau;pMAPT/pTAU;TAU and MAPT;N/A;AI413597;AW045860;FLJ31424;FTDP 17;G protein beta1/gamma2 subunit interacting factor 1;included;MGC134287;MGC138549;MGC156663;Microtubule associated protein tau;Microtubule associated protein tau isoform 4;Mtapt;Paired helical filament tau;PHF tau;Protein phosphatase 1;pTau;regulatory subunit 103;RNPTAU;Tauopathy and respiratory failure

Research Areas:Neuroscience;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC;IF;FCM

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A803

UNIProt ID:P10636

Accession:

Background:Promotes microtubule assembly and stability and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Concentration:1 mg/mL

Immunogen:phosphorylated human Tau (Ser199) peptide

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:3000;IHC 1:200-1:1000;IF 1:50;FCM 1:50-1:100

Calculated MW:79 kDa

ObservedMW:55 kDa