Recombinant Phospho-STAT3 (Ser727) Monoclonal Antibody

SKU: AN301146L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Stat3

Target Synonym:STAT;Signal Transducer and Activator of Transcription;ADMIO;ADMIO1;APRF;HIES;STAT3;Acute-Phase Response Factor;Signal Transducer and Activator of Transcription 3;1110034C02Rik;Acute Phase Response Factor;AW109958;DNA binding protein APRF;FLJ20882;MGC16063;Signal transducer and activator of transcription 3 (acute phase response factor);STAT 3

Research Areas:Signal Transduction;Epigenetics and Nuclear Signaling;Stem Cells;Cancer;Cardiovascular;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6H7

UNIProt ID:P40763

Accession:

Background:The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein.

Concentration:0.2 mg/mL

Immunogen:A synthetic peptide corresponding to residues around (Ser727) of Human Phospho-STAT3

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:400-1:1000;WB 1:2000-1:10000

Calculated MW:88 kDa

ObservedMW:88 kDa