Recombinant Phospho-MEK1/2 (Ser217, 2210) Monoclonal Antibody

SKU: AN300366L

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:MAP2K1

Target Synonym:MEK;MKK;CFC;MAPKK;PRKMK;MAP2K;CFC3;MAPKK1;MEK1;MKK1;PRKMK1;MAP2K1;Dual specificity mitogen activated protein kinase kinase 1;Dual specificity mitogen-activated protein kinase kinase 1;ERK activator kinase 1;kinase 1;MAP kinase kinase 1;MAP kinase/Erk kinase 1;MAPK/ERK kinase 1;MAPKK 1;MEK 1;MEKK1;Mitogen activated protein kinase kinase 1;MKK 1;MP2K1;Protein kinase mitogen activated;Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1)

Research Areas:Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG

Clonality:Monoclonal

Clone NO.:11A4

UNIProt ID:Q02750

Accession:

Background:The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Concentration:1 mg/mL

Immunogen:A synthetic phosphopeptide corresponding to residues around Ser218 and Ser222 of the Human MEK1

Buffer:10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Purification method:Protein A

Dilution:WB 1:2000-1:20000

Calculated MW:43 kDa

ObservedMW:43 kDa