Recombinant Phospho-BRD2 (S37) Monoclonal Antibody

SKU: AN302085L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies;Acetyl/Phospho/Methyl Antibodies

Abbreviation:Phospho-BRD2 (S37)

Target Synonym:RNF;BRD;FSRG;RING;KIAA;BRD2-IT;BRD2;BRD2-IT1;D6S113E;FSH;FSRG1;NAT;O27.1.1;RING3;RNF3;KIAA9001

Research Areas:Cell Biology;Signal Transduction;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A809

UNIProt ID:P25440

Accession:

Background:Brd2 is a highly conserved member of the BET subfamily of bromodomain proteins that contain two tandem N-terminal bromodomains and a single C-terminal extra-terminal (ET) domain. In addition to its involvement in guiding the expression of cell cycle genes through its binding to multiple E2Fs, Brd2 has been shown to be associated with several regulators of transcription, including TFIID and Swi/Snf complexes. First identified as a nuclear serine/threonine kinase, Brd2, like other bromodomain proteins, is thought to function in mammalian development by regulating chromatin structure and transcription. Brd2 has been shown to bind to histone H4 via acetylated Lys12, a substrate of several histone acetyltransferase transcriptional coactivators.

Concentration:1 mg/mL

Immunogen:Recombinant human BRD2 (phospho S37) fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:4000-1:20000

Calculated MW:88 kDa

ObservedMW:110 kDa