Recombinant Phospho-Bad (Ser99) Monoclonal Antibody

SKU: AN300150L

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:Bad

Target Synonym:BCL2L;BBC;BAD;BBC2;BCL2L8;BBC6;AI325008;BBC 2;Bcl 2 Antagonist of Cell Death;Bcl 2 Binding Component 6;BCL X/BCL 2 Binding Protein;BCL X Binding Protein;Bcl XL/Bcl 2 Associated Death Promoter;Bcl2 antagonist of cell death;BCL2 antagonist of cell death protein;BCL2 associated agonist of cell death;Bcl2 Associated Death Promoter;BCL2 binding component 6;BCL2 binding protein;Bcl2 Like 8 Protein;Bcl-2-binding component 6;Bcl2-L-8;Bcl-2-like protein 8;Bcl-XL/Bcl-2-associated death promoter;Proapoptotic BH3 Only Protein

Research Areas:Cell Biology;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:4B16

UNIProt ID:Q92934

Accession:

Background:The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-1, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Concentration:1 mg/mL

Immunogen:A synthetic peptide corresponding to the residues around Ser99 of Human Phospho-Bad

Buffer:10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Purification method:Protein A

Dilution:WB 1:1000-1:20000;

Calculated MW:18 kDa

ObservedMW:18 kDa