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GeneBio Systems

Recombinant Phospho-ATM (Ser1981) Monoclonal Antibody

Recombinant Phospho-ATM (Ser1981) Monoclonal Antibody

AN301139L

£256.00 GBP
£256.00 GBP
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Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Atm

Target Synonym:TEL;TELO;AT1;ATA;ATC;ATD;ATDC;ATE;TEL1;TELO1;ATM;AT mutated;A-T mutated;A-T mutated homolog;Ataxia telangiectasia mutated;Ataxia telangiectasia mutated gene;Ataxia telangiectasia mutated homolog;Ataxia telangiectasia mutated homolog (human);ATM serine/threonine kinase;DKFZp781A0353;homolog;MGC74674;OTTHUMP00000232981;Serine protein kinase ATM;Serine/threonine-protein kinase ATM;Serine-protein kinase ATM;Tefu;Telomere fusion protein;telomere maintenance 1

Research Areas:Epigenetics and Nuclear Signaling;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11A9

UNIProt ID:Q13315

Accession:

Background:The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

Concentration:0.2 mg/mL

Immunogen:A synthetic peptide corresponding to residues around (Ser1981) of Human Phospho-ATM

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000;WB 1:10000-1:50000

Calculated MW:351 kDa

ObservedMW:351 kDa

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