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GeneBio Systems

Recombinant PGK1 Monoclonal Antibody

Recombinant PGK1 Monoclonal Antibody

SKU:AN301286L

Regular price £256.00 GBP
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Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:PGK1

Target Synonym:PGK;MIG;PRP;Phosphoglycerate kinase;Primer recognition protein;OK/SW-cl;Cell migration-inducing gene 10 protein;Epididymis secretory sperm binding protein Li 68p;HEL S 68p;MGC117307;MGC8947;Phosphoglycerate kinase 1;Primer recognition protein 2;PRP 2;PGKA;PGK1;MIG10;OK/SW-cl.110;PGK1

Research Areas:Cardiovascular;Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:4D3

UNIProt ID:P00558

Accession:

Background:The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human PGK1 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:1000-1:4000

Calculated MW:

ObservedMW:

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