Recombinant PAX8 Monoclonal Antibody

SKU: AN301620L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:PAX8

Target Synonym:Paired box;Paired box gene;Paired domain gene;paired box homeotic gene;PAX;PAX8;OTTHUMP00000158659;OTTHUMP00000158660;OTTHUMP00000203723;OTTHUMP00000203724;Paired box 8;Paired box gene 8;paired box homeotic gene 8;Paired box protein Pax 8;Paired box protein Pax-8;Paired domain gene 8;PAX 8

Research Areas:Neuroscience;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:IHC;IF

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A323

UNIProt ID:Q06710

Accession:

Background:PAX8 is one of nine transcription factors within the PAX gene family. It has been observed to be expressed during embryonic development however expression attenuates after development in all but a few tissues. Research has indicated that over-expression of PAX proteins in general are not an initiating event in tumorgenesis however they may facilitate malignant development. PAX8 is expressed in 80-96% of all High-grade serous carcinomas (HGSC) and is commonly used as a marker for the disease. In addition PAX8 has become a useful biomarker for differentiating between mullerian mucinous and non-mullerian tumors. PAX8 has also been associated with neoplasms in the kidney and thyroid.

Concentration:1 mg/mL

Immunogen:Recombinant human PAX8 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:IHC 1:50-1:100;IF 1:50

Calculated MW:

ObservedMW: