Recombinant p53 Monoclonal Antibody

SKU: AN301337L

Size::

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:p53

Target Synonym:BCC;LFS;TRP;BMFS;Antigen NY-CO;Tumor protein;Phosphoprotein p;Tumor suppressor p;Mutant tumor protein;Cellular tumor antigen p;Transformation related protein;BCC7;LFS1;P53;TRP53;TP53;BMFS5;Antigen NY-CO-13;Cellular tumor antigen p53;FLJ92943;Mutant tumor protein 53;p53 tumor suppressor;Phosphoprotein p53;Transformation related protein 53;Tumor protein 53;Tumor protein p53;Tumor suppressor p53;BCC7;LFS1;P53;TRP53;tumor protein p53;Antigen NY-CO-13;BCC7;Cellular tumor antigen p53;FLJ92943;LFS1;Mutant tumor protein 53;p53;p53 tumor suppressor;P53;Phosphoprotein p53;Tp53;Transformation related protein 53;TRP53;Tumor protein 53;Tumor protein p53;Tumor suppressor p53

Research Areas:Cell Biology;Epigenetics and Nuclear Signaling;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:9A10

UNIProt ID:P04637

Accession:

Background:TP53(tumor protein p53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).

Concentration:0.2 mg/mL

Immunogen:Recombinant Human p53 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:44 kDa

ObservedMW:53 kDa