Recombinant NDUFA1 Monoclonal Antibody

SKU: AN300778L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:NDUFA1

Target Synonym:ZNF;NDUFA;NDUFA1;CI-MWFE;MWFE;ZNF183;B. taurus;CI MWFE;Complex I MWFE;complex I MWFE subunit;Complex I-MWFE;homolog of;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 7.5kDa;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1;NADH oxidoreductase subunit MWFE;NADH ubiquinone oxidoreductase (complex 1);NADH ubiquinone oxidoreductase MWFE subunit;NADH-ubiquinone oxidoreductase 1 alpha subcomplex;NADH-ubiquinone oxidoreductase MWFE subunit;NDUA1;NDUFA 1;Type I dehydrogenase;ZNF 183

Research Areas:Tags & Cell Markers;Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:5D3

UNIProt ID:O15239

Accession:

Background:The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human NDUFA1 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-5000

Calculated MW:

ObservedMW:8 kDa