Recombinant N6-methyladenosine (m6A) Monoclonal Antibody

SKU: AN301128L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Acetyl/Phospho/Methyl Antibodies;Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:N6-methyladenosine

Target Synonym:N6-methyladenosine;m6A

Research Areas:

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Species independent

Application:Dot blot

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:12G11

UNIProt ID:/

Accession:

Background:Discovered in the 1970s, m6A is the most prevalent internal modification in polyadenylated mRNAs and long non-coding RNAs (lncRNAs) in higher eukaryotes. m6A is widely conserved among eukaryotic species that range from yeast, plants, flies to mammals, as well as among viral RNAs with a nuclear phase. The m6A-based modification is associated with a well-defined RNA motif, RRACH (R: A/G, H: A/C/U). As a representative of the epitranscriptome, m6A mRNA modifications participate in many vital activities in the cell, including stem cell self-renewal and differentiation, mRNA transcription, alternative splicing, nuclear export, translation, degradation, and microRNA processing. These processes determine the expression or inactivation of specific genes, which is vital for growth and development.(PMID: 30416848; PMID: 24662220; PMID: 30429466)

Concentration:0.2 mg/mL

Immunogen:Recombinant N6-methyladenosine (m6A) protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:DB 1:500-1:2000;

Calculated MW:

ObservedMW: