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GeneBio Systems

Recombinant MUC1 Monoclonal Antibody

Recombinant MUC1 Monoclonal Antibody

AN301606L

£302.00 GBP
£302.00 GBP
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Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:MUC1

Target Synonym:MAM;CA 15;MUC;ADMCKD;ADMCKD1;CA 15-3;CD227;EMA;H23AG;KL-6;MAM6;MCD;MCKD;MCKD1;MUC-1;MUC-1/SEC;MUC-1/X;MUC1/ZD;PEM;PEMT;PUM;MUC1;CA15-3;mucin-1;CA15 3;CA153;Episialin;Carcinoma associated mucin;MUC 1;MUC1 beta;MUC1 CT;MUC1 NT;Mucin 1;Peanut reactive urinary mucin;Polymorphic epithelial mucin;Tumor associated mucin;MUC1/CA15-3 C-terminal;EMA;mucin 1;Breast carcinoma-associated antigen DF3;Cancer antigen 15-3;Carcinoma-associated mucin;Krebs von den Lungen-6;Peanut-reactive urinary mucin;Tumor-associated epithelial membrane antigen;Tumor-associated mucin

Research Areas:Tags & Cell Markers;Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A309

UNIProt ID:P15941

Accession:

Background:The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

Concentration:1 mg/mL

Immunogen:Recombinant human MUC1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:200-1:1000

Calculated MW:17 kDa

ObservedMW:24 kDa

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