Recombinant MTCO2 Monoclonal Antibody

SKU: AN301103L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:MTCO2

Target Synonym:COX;Mtco;Cytochrome c oxidase subunit;MT-CO;MT CO;MT-CO2;COII;MTCO2;COX2;Cytochrome c oxidase II;Cytochrome c oxidase polypeptide II;Cytochrome c oxidase subunit 2;MT CO2;COXII;COX2;COX2;COXII;Cytochrome c oxidase II;MT-CO2;COII;COX2

Research Areas:Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:10F7

UNIProt ID:P00403

Accession:

Background:Cofactor:Copper A.,disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood.,disease:Defects in MT-CO2 are associated with tumor formation.,Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.,similarity:Belongs to the cytochrome c oxidase subunit 2 family.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human MTCO2 rabbit protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1000;WB 1:1000-5000

Calculated MW:26 kDa

ObservedMW:21 kDa