Recombinant MSH2 Monoclonal Antibody

SKU: AN301604L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:MSH2

Target Synonym:FCC;MSH;COCA;LCFS;mutS homolog;MSH2;COCA1;FCC1;HNPCC;HNPCC1;LCFS2;mutS homolog 2;COCA1;FCC1;HNPCC;HNPCC1;LCFS2;mutS homolog 2;MSH2;COCA1;FCC1;HNPCC;HNPCC1;LCFS2

Research Areas:Epigenetics and Nuclear Signaling;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;IHC;IF;IP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A307

UNIProt ID:P43246

Accession:

Background:This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Concentration:1 mg/mL

Immunogen:Recombinant human MSH2 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50;IF 1:50-1:100;IP 1:50-1:100

Calculated MW:105 kDa

ObservedMW:104 kDa