Recombinant Mouse ST6GALNAC2 Protein (His Tag)

SKU: PKSM041361

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: ST6GALNAC2

Target Synonym: 3-GalNAc alpha-2;6-sialyltransferase;6-sialyltransferase II;Gal-beta-1;GalNAc alpha-2;II;SIAT7-B;ST6GalNAc;ST6GalNAc II;Sialyltransferase 7B;Siat7;Siat7b

Research Areas:

Conjugation:

Target Species: Mouse

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: P70277

Accession: P70277

Background: Alpha-N-acetylgalactosaminide alpha -2,6-sialyltransferase 2, is a type II membrane protein localized in the Golgi network and catalyzes 2,6-sialylation of the Tn antigen. Sialyl-Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis. It has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine.

Concentration:

Activity: Not validated for activity

Sequence: Ser28-Arg373

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 50mMTris,150mMNaCl,pH7.5.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 40.4 kDa

ObservedMW: 45 kDa