Recombinant Mouse MCP-1 Protein(Sumo Tag)

SKU: PDEM100337

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Cytokines

Abbreviation:MCP-1

Target Synonym:CCL2;Monocyte chemoattractant protein-1;SCYA2;HC11

Research Areas:Immunology;Cardiovascular;Cancer

Conjugation:

Target Species:Mouse

Expression Host:E.coli

Application:

Fusion tag:N-Sumo

UNIProt ID:P10148

Accession:P10148

Background:Monocyte chemoattractant protein 1(CCL2/JE/MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. CCL2/JE/MCP-1 protein interacts with chemokine C-C motif receptor 2(CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of CCL2/JE/MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.

Concentration:

Activity:Not validated for activity

Sequence:Gln24-Arg96

Purity:> 95% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method

Calculated MW:20.9 kDa

ObservedMW:32 kDa