Recombinant Mouse IL7RA/CD127 Protein (Fc Tag)

SKU: PKSM041242

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: IL7RA;CD127

Target Synonym: CD127;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7RA;IL-7Ralpha;IL-7R-alpha;Interleukin-7 receptor subunit alpha;Il7r

Research Areas:

Conjugation:

Target Species: Mouse

Expression Host: HEK293 Cells

Application: BLI

Fusion tag: C-Fc

UNIProt ID:

Accession: P16872

Background: Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.

Concentration:

Activity: Loaded Human IL-7-His on HIS1K Biosensor, can bind Mouse IL-7RA-Fc with an affinity constant of 5.91 nM as determined in BLI assay.

Sequence: Glu21-Asp239

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Sucrose, 3% Glycine, 100mM NaCl, 0.1mM EDTA, 0.05% Tween 80, pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 52.1 kDa

ObservedMW: 61-75 kDa