Recombinant Mouse FGF-10/KGF-2 protein

SKU: CD00457

Size:5 ug

Background:Fibroblast growth factor 10 belongs to the fibroblast growth factor (FGF) family, which is involved in a variety of biological processes such as embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. Like most other FGF family members, FGF-10 also has a heparin-binding domain and plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. In addition, FGF-10 may take parts in wound healing and is required for normal branching morphogenesis. Recombinant Mouse FGF-10 contains a 173 amino acids and it shares 93 % and 90 % a.a. sequence identity with human and rat FGF-10.

Research_area:Immunology

Purity:> 95 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Mouse Fibroblast Growth Factor-10

Biological activity:Fully biologically active when compared to standard. The ED5 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than .5 ng/ml, corresponding to a specific activity of > 2. × 16 IU/mg.

Synonyms:FGF-1/KGF-2,FGF1,AEY1, AEY17, BB213776, Fgf-1, Fgf5a, Gsfaey, Gsfaey17, Mouse

Endotoxin:Less than 1 EU/μg of rMuKGF-2/FGF-10 as determined by LAL method.

Storage:-20ºC

Sequence:QALGQDMVSQ EATNCSSSSS SFSSPSSAGR HVRSYNHLQG DVRWRRLFSF TKYFLTIEKN GKVSGTKNED CPYSVLEITS VEIGVVAVKA INSNYYLAMN KKGKLYGSKE FNNDCKLKER IEENGYNTYA SFNWQHNGRQ MYVALNGKGA PRRGQKTRRK NTSAHFLPMT IQT

uniprot accession: O35565

Molecular weight:Approximately19.5 kDa, a single non-glycosylated polypeptide chain containing 173 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in 2 × PBS, 6 mM NaCl, pH 7.4, 1 mM mercaptoethanol.