Recombinant Mouse Eotaxin/CCL11 protein

SKU: CD00474

Size:5 ug

Background:Mouse CCL11 is belonging to the CC chemokine family. CCL11 was first purified from bronchoalveolar lavage fluid of guinea pigs. It was a strong and specific eosinophil chemoattractant in vitro. It can directly chemotactic for eosinophils, but not for monocytes or neutrophils. Mouse CCL11 is approximately 63 % identical at the amino acid level to human CCL11. In addition, CCL11 also shows about 60 % amino acid sequence identity to human MCPs. CCR3 has been identified to be a specific CCL11 receptor.

Research_area:Immunology

Purity:> 96 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Mouse Eotaxin/CCL11

Biological activity:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration range of 1-1 ng/ml.

Synonyms:Eotaxin/CCL11, Scya, Scya11, eot, eotaxin,Mouse

Endotoxin:Less than 1 EU/μg of rMuEotaxin/CCL11 as determined by LAL method.

Storage:-20ºC

Sequence:HPGSIPTSCC FIMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTRLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP

uniprot accession:P48298

Molecular weight:Approximately 8.4 kDa, a single non-glycosylated polypeptide chain containing 74 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in PBS, pH 7.4.