Recombinant Mouse CD74 Protein (mFc & His Tag)

SKU: PKSM041039

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: CD74

Target Synonym: CD74 antigen;CD74 molecule;Cluster of Differentiation 74;DHLAG gamma chain of class II antigens;HLA class II histocompatibility antigen gamma chain;HLA-DR antigens-associated invariant chain;HLADG;class II invariant chain;major histocompatibility complex

Research Areas:

Conjugation:

Target Species: Mouse

Expression Host: HEK293 Cells

Application:

Fusion tag: C-mFc-His

UNIProt ID: P04441

Accession: P04441-2

Background: Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.

Concentration:

Activity: Not validated for activity

Sequence: Gln56-Leu215

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.5.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 44.5 kDa

ObservedMW: 45-55 kDa