Recombinant MCM3 Monoclonal Antibody

SKU: AN301597L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:MCM3

Target Synonym:HCC;DNA replication licensing factor MCM;DNA polymerase alpha holoenzyme-associated protein P;P1-MCM;MCM;MCM3;HCC5;P1-MCM3;P1.h;RLFB;MCM 3;P1 Protein;P102 protein;p102;DNA replication licensing factor MCM3;DNA polymerase alpha holoenzyme-associated protein P1;RLF subunit beta;Cervical cancer proto oncogene 5;DNA polymerase alpha holoenzyme associated P1;DNA polymerase alpha holoenzyme associated protein P1;DNA replication factor MCM3;HCC 5;hRlf beta subunit;Human cervical cancer proto oncogene 5;MCM3 minichromosome maintenance deficient 3;MGC1157;Minichromosome maintenance complex component 3;Minichromosome maintenance deficient 3;Minichromosome maintenance protein 3;P1 h;P1 MCM3;Replication licensing factor beta subunit;RLF beta subunit

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC;IP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A296

UNIProt ID:P25205

Accession:

Background:Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.

Concentration:1 mg/mL

Immunogen:Recombinant human MCM3 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000;IHC 1:200-1:1000;IP 1:25-1:100

Calculated MW:91 kDa

ObservedMW:100 kDa