Recombinant MAX/MYC associated factor X Monoclonal Antibody

SKU: AN300263P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:MAX

Target Synonym:bHLHd;MAX;bHLHd4;Class D Basic Helix-Loop-Helix Protein 4;Myc-Associated Factor X;Protein Max

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;FCM;ICC/IF;IP

Isotype:IgG

Clonality:Monoclonal

Clone NO.:11B4

UNIProt ID:P61244

Accession:

Background:The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 4. Alternative splicing results in multiple transcript variants.

Concentration:1 mg/mL

Immunogen:Recombinant Human MAX / MYC associated factor X protein

Buffer:0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0

Purification method:Protein A

Dilution:WB 1:500-1:1000;FCM 1:100-1:500;ICC/IF 1:100-1:500;IP 0.2-1 μL/mg of lysate

Calculated MW:18 kDa

ObservedMW:20 kDa