Recombinant LRP6 Monoclonal Antibody

SKU: AN300719L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:LRP6

Target Synonym:LRP;ADCAD;STHAG;LRP6;ADCAD2;STHAG7;C030016K15Rik;FLJ90062;FLJ90421;LDL receptor related protein 6;Low density lipoprotein receptor related protein 6;Low-density lipoprotein receptor-related protein 6;LRP-6;OTTHUMP00000238979;OTTHUMP00000238980;OTTHUMP00000238982

Research Areas:Signal Transduction;Stem Cells;Cardiovascular;Neuroscience;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:11A1

UNIProt ID:O75581

Accession:

Background:This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human LRP6 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:180 kDa

ObservedMW:210 kDa