Recombinant LIFR/CD118 Monoclonal Antibody

SKU: AN300079P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:LIFR

Target Synonym:SJS;LIFR;CD118;LIF-R;SJS2;STWS;SWS;gp190

Research Areas:Immunology;Stem Cells;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC-P

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:12G5

UNIProt ID:P42702

Accession:

Background:This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 2, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.

Concentration:1 mg/mL

Immunogen:Recombinant Human LIFR protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:100-1:500;

Calculated MW:

ObservedMW: