Recombinant KLF4 Monoclonal Antibody

SKU: AN301092L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:KLF4

Target Synonym:KLF;EZF;GKLF;KLF4

Research Areas:Epigenetics and Nuclear Signaling;Stem Cells;Cancer;Cardiovascular;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6A1

UNIProt ID:O43474

Accession:

Background:This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human KLF4 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1000;WB 1:1000-5000

Calculated MW:55 kDa

ObservedMW:60 kDa