Recombinant Insulin Monoclonal Antibody

SKU: AN301325L

Size::

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Insulin

Target Synonym:MODY;IDDM;IDDM1;IDDM2;ILPR;IRDN;MODY10;INS;Insulin;Connecting Peptide;Insulin A chain;Insulin B chain;Preproinsulin;Proinsulin;Proinsulin precursor;IDDM;IDDM1;IDDM2;ILPR;ins;INS;Insulin A chain;Insulin B chain;IRDN;MODY10;Preproinsulin;Proinsulin;Proinsulin precursor;Pro-Insulin

Research Areas:Signal Transduction;Neuroscience;Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:9C4

UNIProt ID:P01308

Accession:

Background:After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Insulin protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-1:5000

Calculated MW:12 kDa

ObservedMW:12 kDa